• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

喂食胡萝卜对二乙基亚硝胺诱导大鼠肝癌的延迟作用。

Delay of diethylnitrosamine-induced hepatoma in rats by carrot feeding.

作者信息

Rieder A, Adamek M, Wrba H

出版信息

Oncology. 1983;40(2):120-3. doi: 10.1159/000225708.

DOI:10.1159/000225708
PMID:6828289
Abstract

Carcinogenesis and death caused by diethylnitrosamine(DENA)-induced hepatomas in Sprague Dawley rats can be significantly delayed by feeding only carrots for several days a week. As this result is not obtained by supplementing food with even higher concentrations of synthetic beta-carotene, there must be several other factors which--together with the carotenoid--contribute to the positive effect. Several other possibilities such as effects of fasting, direct interactions with the carcinogen, resorption, vitamin A storage in the liver, etc., are proposed and discussed.

摘要

每周仅喂几天胡萝卜,可显著延缓二乙基亚硝胺(DENA)诱导的斯普拉格-道利大鼠肝癌的致癌过程和死亡。由于即使在食物中添加更高浓度的合成β-胡萝卜素也无法获得这一结果,所以必定还有其他几种因素——与类胡萝卜素一起——促成了这种积极效果。文中提出并讨论了其他几种可能性,如禁食的影响、与致癌物的直接相互作用、吸收、肝脏中维生素A的储存等。

相似文献

1
Delay of diethylnitrosamine-induced hepatoma in rats by carrot feeding.喂食胡萝卜对二乙基亚硝胺诱导大鼠肝癌的延迟作用。
Oncology. 1983;40(2):120-3. doi: 10.1159/000225708.
2
Effects of discontinuation of chronic feeding of diethylnitrosamine on the development of hepatomas in adult rats.停止长期喂食二乙基亚硝胺对成年大鼠肝癌发生的影响。
Br J Cancer. 1979 Aug;40(2):260-7. doi: 10.1038/bjc.1979.174.
3
Impairment of the mitochondrial respiratory chain activity in diethylnitrosamine-induced rat hepatomas: possible involvement of oxygen free radicals.二乙基亚硝胺诱导的大鼠肝癌中线粒体呼吸链活性受损:氧自由基的可能作用。
Cancer Res. 1995 Jul 15;55(14):3028-35.
4
Hepatocellular carcinoma is induced by a subnecrogenic dose of diethylnitrosamine in previously fasted-refed rats.在先前禁食再喂食的大鼠中,亚致死剂量的二乙基亚硝胺可诱发肝细胞癌。
Nutr Cancer. 1998;32(1):49-54. doi: 10.1080/01635589809514716.
5
Inhibition of the hepatocarcinogenic activity of diethylnitrosamine (DENA) by ethanol in rats.
Hepatogastroenterology. 1981 Oct;28(5):242-4.
6
Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis.在二乙基亚硝胺诱导的化学性大鼠肝癌发生过程中钒对异生物转化酶的选择性诱导及改变的特征研究
Oncol Res. 1999;11(1):41-53.
7
Effects of dietary selenium concentration on the development of enzyme-altered liver foci and hepatocellular carcinoma induced by diethylnitrosamine or N-acetylaminofluorene in rats.膳食硒浓度对二乙基亚硝胺或N-乙酰氨基芴诱导的大鼠酶改变性肝灶和肝细胞癌发生发展的影响。
Cancer Res. 1985 Nov;45(11 Pt 1):5489-95.
8
Combined supplementation of vanadium and beta-carotene suppresses placental glutathione S-transferase-positive foci and enhances antioxidant functions during the inhibition of diethylnitrosamine-induced rat liver carcinogenesis.钒和β-胡萝卜素联合补充可抑制二乙基亚硝胺诱导的大鼠肝癌发生过程中的胎盘谷胱甘肽S-转移酶阳性灶,并增强抗氧化功能。
J Gastroenterol Hepatol. 2004 Jun;19(6):683-93. doi: 10.1111/j.1440-1746.2004.03378.x.
9
Membrane enzyme cytochemical changes in the hepatocytes of diethylnitrosamine induced hepatomas.二乙基亚硝胺诱导的肝癌肝细胞中膜酶细胞化学变化
Arch Geschwulstforsch. 1985;55(2):99-105.
10
Effect of coadministration of phenobarbital sodium on N-nitrosodiethylamine-induced gamma-glutamyltransferase-positive foci and hepatocellular carcinoma in rats.苯巴比妥钠联合给药对N-亚硝基二乙胺诱导的大鼠γ-谷氨酰转移酶阳性灶和肝细胞癌的影响。
J Natl Cancer Inst. 1984 Mar;72(3):741-4.

引用本文的文献

1
Vegetables, fruit, and cancer. I. Epidemiology.蔬菜、水果与癌症。I. 流行病学
Cancer Causes Control. 1991 Sep;2(5):325-57. doi: 10.1007/BF00051672.
2
Vegetables, fruit, and cancer. II. Mechanisms.蔬菜、水果与癌症。II. 作用机制。
Cancer Causes Control. 1991 Nov;2(6):427-42. doi: 10.1007/BF00054304.