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Inhibition of the hepatocarcinogenic activity of diethylnitrosamine (DENA) by ethanol in rats.

作者信息

Habs M, Schmähl D

出版信息

Hepatogastroenterology. 1981 Oct;28(5):242-4.

PMID:7345007
Abstract

Male Sprague-Dawley rats received 0.1 mg/kg of diethyl-nitrosamine orally five times a week for life with or without additional subsequent administration of 5 ml/rat/day of a 25% aqueous solution of ethanol. The additional treatment with ethanol significantly reduced the induction of liver cancer, but not of esophageal tumors. These findings do not support speculations based on epidemiologic studies as to a cancer-causing effect of alcohol.

摘要

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