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人类右颈动脉分叉处早期动脉粥样硬化病变的定位

Localization of early atherosclerotic lesions in the right carotid bifurcation in humans.

作者信息

Grøttum P, Svindland A, Walløe L

出版信息

Acta Pathol Microbiol Immunol Scand A. 1983 Jan;91(1):65-70. doi: 10.1111/j.1699-0463.1983.tb02727.x.

DOI:10.1111/j.1699-0463.1983.tb02727.x
PMID:6829313
Abstract

The detailed localization of early atherosclerotic lesions in the right carotid bifurcation was studied in 37 carotid arteries obtained from autopsies of young persons who had suffered a violent and sudden death. Drawings of the sudanophilic lesions in the vessel wall were fed to a computer, scaled to a standardized size and shape, and added together. The results are presented as contour lines connecting points with equal frequency of early lesions. The distribution of early lesions reveals a distinct pattern: The early lesions start to develop on the outer walls of the bifurcation, while the inner walls downstream from the flow divider are left free, as are also the lateral walls. In the carotid sinus the distribution of the lesions has a U-formed pattern.

摘要

对37条从遭受暴力猝死的年轻人尸体解剖中获取的颈动脉进行研究,以确定右颈动脉分叉处早期动脉粥样硬化病变的详细定位。将血管壁上嗜苏丹病变的绘图输入计算机,按标准化大小和形状进行缩放,然后相加。结果以连接早期病变频率相等的点的等高线表示。早期病变的分布呈现出一种独特的模式:早期病变开始在分叉处的外壁发展,而分流器下游的内壁以及侧壁则未出现病变。在颈动脉窦中,病变的分布呈U形模式。

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引用本文的文献

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Haemodynamic Wall Shear Stress, Endothelial Permeability and Atherosclerosis-A Triad of Controversy.血流动力学壁面剪应力、内皮通透性与动脉粥样硬化——争议三联症
Front Bioeng Biotechnol. 2022 Mar 7;10:836680. doi: 10.3389/fbioe.2022.836680. eCollection 2022.
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Topographical study on arteriosclerotic lesions at the bifurcations of human cerebral arteries.人脑动脉分叉处动脉硬化病变的局部解剖学研究。
Heart Vessels. 1985 May;1(2):70-3. doi: 10.1007/BF02066351.