Weiner B H, Alpert J S, Dalen J E, Ockene I S
Am Heart J. 1983 Mar;105(3):386-93. doi: 10.1016/0002-8703(83)90354-x.
The response of the right ventricle to exercise was examined in 19 patients with heart disease by constructing right ventricular function curves and determining the relationship between right ventricular afterload and preload. Simultaneous cardiac output and right heart pressures were measured at rest, during exercise, and 10 minutes after exercise. The patients were divided into two groups: those in whom the mean right atrial pressure did not rise above 7 mm Hg during exercise (group I, nine patients) and those in whom this variable did rise above 7 mm Hg (group II, 10 patients). A normal range for right ventricular function curves was derived from data reported in the literature. All of the patients in group I remained within this normal range during exercise. Half the patients in group II, however, fell outside the normal range during exercise. For all 19 patients, a linear relationship existed between right ventricular preload and afterload during exercise with a correlation between right atrial mean pressure and pulmonary arterial systolic pressure of r = 0.86.
通过构建右心室功能曲线并确定右心室后负荷与前负荷之间的关系，对19例心脏病患者右心室对运动的反应进行了研究。在静息状态、运动期间及运动后10分钟测量心输出量和右心压力。患者被分为两组：运动期间平均右心房压力未升至7 mmHg以上的患者（第一组，9例）和该变量升至7 mmHg以上的患者（第二组，10例）。右心室功能曲线的正常范围来自文献报道的数据。第一组所有患者在运动期间均保持在该正常范围内。然而，第二组中有一半患者在运动期间超出了正常范围。对于所有19例患者，运动期间右心室前负荷与后负荷之间存在线性关系，右心房平均压力与肺动脉收缩压之间的相关性为r = 0.86。
