大鼠甲状腺生长的调控——对促激素刺激特异性脱敏的一个例子。
Control of growth in the rat thyroid--an example of specific desensitization to trophic hormone stimulation.
作者信息
Wynford-Thomas D, Stringer B M, Harach H R, Williams E D
出版信息
Experientia. 1983 Apr 15;39(4):421-3. doi: 10.1007/BF01963160.
PMID:6832329
Abstract
Rat thyroid follicular cells desensitized to the mitogenic action of TSH by prolonged stimulation retain the capacity to respond to the mitogenic stimulus of wounding. The implications for thyroid growth control and neoplasia are discussed.
摘要
经长期刺激对促甲状腺激素（TSH）的促有丝分裂作用脱敏的大鼠甲状腺滤泡细胞，仍保留对创伤促有丝分裂刺激作出反应的能力。文中讨论了其对甲状腺生长控制和肿瘤形成的意义。
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