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无菌环境的维持及其临床应用。

Maintenance of germ-free environment and its clinical utility.

作者信息

Nagao T, Ozawa A, Sasaki S

出版信息

Jpn J Clin Oncol. 1983;13 Suppl 1:103-10.

PMID:6834655
Abstract

The level of cleanliness in the laminar airflow room of Tokai University Hospital was studied. Bacteriological monitoring of the protected isolation ward during occupancy by patients revealed that it was kept at class 100 according to NASA standards. The laminar airflow room was decontaminated with formaldehyde gas by means of a gas generator which we made. This decontamination method was shown to be easy and safe to handle, and stable in its effects. Up to December 1981, 54 patients with acute leukemia were treated in the protected isolation ward. The incidence of infection in patients with acute leukemia was lower in the protected isolation ward than in the conventional ward. No respiratory infection was observed in the protected isolation ward. These results demonstrated statistically significant advantages of the use of the laminar airflow room for prevention of infection.

摘要

对东海大学医院层流空气房间的清洁程度进行了研究。对患者入住期间的保护性隔离病房进行细菌学监测发现,根据美国国家航空航天局(NASA)标准,该病房保持在100级。使用我们自制的气体发生器,用甲醛气体对层流空气房间进行净化处理。结果表明,这种净化方法操作简便、安全,效果稳定。截至1981年12月,有54例急性白血病患者在保护性隔离病房接受治疗。急性白血病患者在保护性隔离病房的感染发生率低于传统病房。在保护性隔离病房未观察到呼吸道感染。这些结果证明了使用层流空气房间预防感染具有统计学上的显著优势。

相似文献

1
Maintenance of germ-free environment and its clinical utility.无菌环境的维持及其临床应用。
Jpn J Clin Oncol. 1983;13 Suppl 1:103-10.
2
Comparison of protected isolation techniques between the laminar airflow room and the life island unit.
Tokai J Exp Clin Med. 1981 Oct;6(4):427-33.
3
Comparative study of protected environment for children with malignant disease.恶性疾病患儿保护环境的比较研究。
Jpn J Clin Oncol. 1983;13 Suppl 1:143-9.
4
Application of simplified bioclean apparatuses for treatment of acute leukemia.简化生物净化装置在急性白血病治疗中的应用。
Jpn J Clin Oncol. 1983;13 Suppl 1:133-42.
5
Efficacy of laminar air flow room with or without clean nursing for preventing infection in patients with acute leukemia.层流室加或不加清洁护理对预防急性白血病患者感染的效果。
Jpn J Clin Oncol. 1983;13 Suppl 1:151-7.
6
Techniques and clinical effect of aseptic procedures on patients with acute leukemia in laminar airflow rooms.层流病房中无菌操作对急性白血病患者的技术及临床效果
Jpn J Clin Oncol. 1983;13 Suppl 1:95-102.
7
Clinical use of bioclean rooms in Japan with special reference to medical isolators.日本生物洁净室的临床应用,特别提及医用隔离器。
Jpn J Clin Oncol. 1983;13 Suppl 1:91-4.
8
Infection prevention for patients with acute leukemia using laminar air flow rooms.使用层流室对急性白血病患者进行感染预防。
Tokai J Exp Clin Med. 1986;11 Suppl:9-14.
9
[Proceedings: Experiences with isolation of leukemic patients].[会议记录:白血病患者隔离的经验]
Schweiz Med Wochenschr. 1975 Dec 20;105(51):1792-4.
10
Infection prevention in acute nonlymphocytic leukemia. Laminar air flow room reverse isolation with oral, nonabsorbable antibiotic prophylaxis.急性非淋巴细胞白血病的感染预防。采用层流室反向隔离并进行口服、不可吸收抗生素预防。
Ann Intern Med. 1975 Mar;82(3):351-8. doi: 10.7326/0003-4819-82-3-351.

引用本文的文献

1
Report on the Consensus Workshop on Formaldehyde.甲醛共识研讨会报告
Environ Health Perspect. 1984 Dec;58:323-81. doi: 10.1289/ehp.58-1569424.