Armstrong-Esther C A, Lacey J H, Crisp A H, Bryant T N
Postgrad Med J. 1978 Jun;54(632):395-9. doi: 10.1136/pgmj.54.632.395.
Patients suffering from anorexia nervosa rarely appear to develop the common cold or influenza. This study examines the immunological response of fifteen female anorexia nervosa patients of both the vomiting and carbohydrate-abstaining type and compares them with a control population matched for age and occupation. Both anorectics and control populations received the admune influenza vaccine. Initially both groups had similar haemagglutination inhibition titres against the three different viral antigens: A/HK; A/PC; A/Eng. However, the anorectics showed over a 2-month period a higher titre of antibody especially to the Hong Kong virus: this was sigignificant. Cellular immune responses were measured using a tuberculin and a macrophage inhibition test, no significant difference between the two groups was obderved. These results which support the clinical findings are discussed.
患有神经性厌食症的患者似乎很少患普通感冒或流感。本研究检测了15名呕吐型和戒碳水化合物型的女性神经性厌食症患者的免疫反应，并将她们与年龄和职业相匹配的对照组人群进行比较。厌食症患者和对照组人群都接种了流感疫苗。最初，两组针对三种不同病毒抗原（A/HK；A/PC；A/Eng）的血凝抑制效价相似。然而，在两个月的时间里，厌食症患者对抗体的效价更高，尤其是对香港病毒的抗体效价：这具有显著性。使用结核菌素和巨噬细胞抑制试验测量细胞免疫反应，两组之间未观察到显著差异。对支持临床发现的这些结果进行了讨论。
