Genetic linkage relations of the human plasminogen gene.

No evidence for close linkage was found between the human plasminogen (PLGN) locus and 35 other marker genes using the LIPED 3 computer program of Ott (1974). Although positive lod scores were found for PLGN-GC relations in females, the lack of linkage between the two loci in males demands that the reported assignment of the PLGN locus to chromosome 4 (Eiberg et al. 1981) should be considered with reservations.