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结核菌素皮肤试验中的回忆反应:测量与时间关系。卡介苗接种豚鼠实验。

The anamnestic effect in tuberculin skin testing: measurement and time relations. Experiments in BCG-vaccinated guinea pigs.

作者信息

Lehmann E H

出版信息

Scand J Respir Dis. 1978 Jun;59(3):119-29.

PMID:684383
Abstract

The repeat-test effect, an example of anamnestic effect in cellular immunity, was investigated in BCG-vaccinated guinea pigs, using 25 TU Mantoux tests to influence as well as assess skin reactivity to tuberculin. Two different methods of quantitating the effect were tried and found valuable. The effect could be regularly observed 12 weeks or more after BCG-vaccination, and with less regularly 6 to 9 weeks after BCG-vaccination. The effect was found whether the interval between the first (interim) test and the second (repeat) test was as short as 3 days or as long as 44 weeks.

摘要

在接种卡介苗的豚鼠中研究了重复试验效应(细胞免疫中回忆效应的一个例子),使用25个结核菌素单位的结核菌素试验来影响并评估皮肤对结核菌素的反应性。尝试了两种不同的定量该效应的方法,发现它们很有价值。该效应在卡介苗接种后12周或更长时间可定期观察到,在卡介苗接种后6至9周观察到的频率较低。无论第一次(中期)试验和第二次(重复)试验之间的间隔短至3天还是长达44周,均可发现该效应。

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