心理介导对人类结核菌素迟发型超敏反应的影响。
Psychologically mediated effect on the delayed hypersensitivity reaction to tuberculin in humans.
作者信息
Smith G R, McDaniel S M
出版信息
Psychosom Med. 1983 Mar;45(1):65-70. doi: 10.1097/00006842-198303000-00009.
Abstract
Recent research with animals has indicated a central nervous system effect on the immune system. This report describes findings of a possible psychologically mediated effect on the delayed hypersensitivity reaction to tuberculin in humans. Seven tuberculin positive subjects evidenced a decreased response to tuberculin (as measured by erythema and induration) when a paradigm similar to behavioral conditioning was followed where the subjects expected their reactions to be negative.
摘要
近期对动物的研究表明，中枢神经系统对免疫系统有影响。本报告描述了一项关于人类对结核菌素迟发型超敏反应可能存在心理介导效应的研究结果。七名结核菌素呈阳性的受试者在遵循一种类似于行为条件作用的范式时，即受试者预期自己的反应为阴性时，对结核菌素的反应（通过红斑和硬结测量）有所降低。
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