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梗死心肌的核磁共振成像:大鼠模型

Nuclear magnetic resonance imaging of the infarcted muscle: a rat model.

作者信息

Herfkens R J, Sievers R, Kaufman L, Sheldon P E, Ortendahl D A, Lipton M J, Crooks L E, Higgins C B

出版信息

Radiology. 1983 Jun;147(3):761-4. doi: 10.1148/radiology.147.3.6844611.

DOI:10.1148/radiology.147.3.6844611
PMID:6844611
Abstract

Eleven Sprague-Dawley rats with experimentally produced infarction of the lower extremities were imaged by nuclear magnetic resonance (NMR) immediately after infarction, and 6 and 24 hours later. Contrast between the infarcted and control muscles was noted immediately and continued to increase through 24 hours. These changes corresponded to a significant increase in the water content of the infarcted extremity at 24 hours. These results suggest promise for NMR imaging in the identification of myocardial infarction and should encourage further investigation in this area.

摘要

11只实验性造成下肢梗死的Sprague-Dawley大鼠在梗死后即刻、6小时和24小时后接受了核磁共振(NMR)成像。梗死肌肉与对照肌肉之间的对比度在梗死后即刻就被观察到,并持续增加至24小时。这些变化与梗死肢体在24小时时含水量的显著增加相对应。这些结果表明NMR成像在识别心肌梗死方面具有前景,并应鼓励在该领域进行进一步研究。

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