Popescu I G, Comes I, Costescu M, Murariu D, Ulmeanu V
Med Interne. 1983 Jan-Mar;21(1):13-7.
The present investigation was suggested by the fact that bronchial asthma (of all types) presents in Craiova and the district of Dolj a relatively increased incidence which may be correlated with certain findings concerning the incidence of atmospheric fungi in the houses and working places of asthmatic subjects. Petri dishes with Czapek medium were exposed monthly in the open air, in 17 houses of asthmatic subjects and in a large bakery unit. The prevalence of various types of fungi was observed on the culture media and a correlation could be made with the seasons. In the houses of asthmatics Penicillium was found to predominate and in certain months of the year Aspergillus as well, which may have a certain etiopathogenic role in bronchial asthma. In certain months Cladosporium and Alternaria also appeared. In the open air the number of colonies was smaller but the incidence was identical. In the bakery unit Penicillium was predominant in 3 out of 5 months, Aspergillus prevailling in all the other months of the year. Cladosporium and Alternaria were also rather frequent. Other fungi sometimes found in relatively large proportions (Mucor, Rhizopus, Verticillium) were not in themselves etiopathogenically involved in bronchial asthma.
在克拉约瓦和多尔日县，所有类型的支气管哮喘发病率相对较高，这可能与哮喘患者家中及工作场所大气真菌发病率的某些调查结果相关。装有察氏培养基的培养皿每月暴露于户外、17位哮喘患者家中以及一家大型面包厂。在培养基上观察到各类真菌的流行情况，并与季节建立了相关性。在哮喘患者家中，发现青霉占主导，在一年中的某些月份曲霉也占主导，它们可能在支气管哮喘中具有一定的病因作用。在某些月份，枝孢菌和链格孢菌也会出现。户外菌落数量较少，但发病率相同。在面包厂，青霉在5个月中的3个月占主导，曲霉在一年中的所有其他月份占主导。枝孢菌和链格孢菌也相当常见。其他有时发现比例相对较高的真菌（毛霉、根霉、轮枝菌）本身与支气管哮喘的病因无关。
