• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

西咪替丁与慢性肝病中的门静脉压力

Cimetidine and portal pressure in chronic liver disease.

作者信息

Cole M J, Shapero T F, Saibil E A

出版信息

Can Med Assoc J. 1983 Jan 15;128(2):131-2.

PMID:6848155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1874813/
Abstract

Portal pressure was determined in 10 patients with chronic liver disease before and after an infusion of cimetidine. The drug had no significant effect on portal hypertension. Suggestions that histamine H2-receptor antagonists, by decreasing portal pressure, may be useful in the management of bleeding from esophageal varices are not supported by these results.

摘要

在10例慢性肝病患者中，于静脉输注西咪替丁前后测定门静脉压力。该药物对门静脉高压无显著影响。组胺H2受体拮抗剂通过降低门静脉压力可能有助于治疗食管静脉曲张出血的观点未得到这些结果的支持。

相似文献

1
Cimetidine and portal pressure in chronic liver disease.西咪替丁与慢性肝病中的门静脉压力
Can Med Assoc J. 1983 Jan 15;128(2):131-2.
2
[Effect of cimetidine on wedged hepatic venous pressure in cirrhotic patients].[西咪替丁对肝硬化患者肝静脉楔压的影响]
Zhonghua Wai Ke Za Zhi. 1991 Aug;29(8):500-2, 525-6.
3
Effect of cimetidine on portal hypertension in cirrhotic patients.西咪替丁对肝硬化患者门静脉高压的影响。
Br Med J (Clin Res Ed). 1982 Apr 17;284(6323):1159-60. doi: 10.1136/bmj.284.6323.1159-a.
4
Effect of cimetidine on wedged hepatic venous pressure in cirrhotic patients.西咪替丁对肝硬化患者肝静脉楔压的影响。
Chin Med J (Engl). 1991 Mar;104(3):186-90.
5
Effects of cimetidine and ranitidine on splanchnic hemodynamics in patients with chronic liver disease.西咪替丁和雷尼替丁对慢性肝病患者内脏血流动力学的影响。
Am J Gastroenterol. 1985 Apr;80(4):290-3.
6
Effect of phenoxybenzamine (POB) on portal venous pressure in patients with portal hypertension.苯苄胺（POB）对门静脉高压症患者门静脉压力的影响。
Am J Gastroenterol. 1979 Apr;71(4):389-94.
7
[The effects of cimetidine on splanchnic hemodynamics in cirrhotic patients with portal hypertension].
Zhonghua Wai Ke Za Zhi. 1993 Apr;31(4):207-9.
8
[Computed sonography observation on the effects of cimetidine on the liver blood flow in cirrhotic patients with portal hypertension].
Zhonghua Wai Ke Za Zhi. 1995 Aug;33(8):466-9.
9
Direct transhepatic measurement of portal vein pressure using a thin needle. Comparison with wedged hepatic vein pressure.使用细针经肝直接测量门静脉压力。与肝静脉楔压的比较。
Gastroenterology. 1977 Apr;72(4 Pt 1):584-9.
10
[Portal vein hypertension in chronic liver diseases].[慢性肝病中的门静脉高压症]
Fortschr Med. 1981 Dec 3;99(45):1900-4.

本文引用的文献

1
Reduction of liver blood flow and propranolol metabolism by cimetidine.西咪替丁对肝血流量及普萘洛尔代谢的影响
N Engl J Med. 1981 Mar 19;304(12):692-5. doi: 10.1056/NEJM198103193041202.
2
Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis: a controlled study.普萘洛尔预防肝硬化患者复发性胃肠道出血的对照研究。
N Engl J Med. 1981 Dec 3;305(23):1371-4. doi: 10.1056/NEJM198112033052302.
3
Evidence for both histamine H1- and H2-receptors in the gastric vasculature of the cat.猫胃血管中组胺H1和H2受体的证据。
Br J Pharmacol. 1980 May;69(1):21-7. doi: 10.1111/j.1476-5381.1980.tb10878.x.
4
Effect of histamine and histamine antagonists on portal blood pressure in patients with hepatosplenic schistosomiasis.组胺及组胺拮抗剂对肝脾型血吸虫病患者门静脉血压的影响
Br J Clin Pharmacol. 1980 Aug;10(2):157-61. doi: 10.1111/j.1365-2125.1980.tb01733.x.
5
Portal and systemic effects of selective infusion of vasopressin into the superior mesenteric artery in cirrhotic patients.肝硬化患者肠系膜上动脉选择性输注血管加压素的门静脉和全身效应
Gastroenterology. 1975 Jul;69(1):6-12.
6
Histamine H1- and H2-receptor vasodilation of canine intestinal circulation.组胺H1和H2受体对犬肠道循环的血管舒张作用。
Am J Physiol. 1977 Sep;233(3):E219-24. doi: 10.1152/ajpendo.1977.233.3.E219.
7
Wedged and free hepatic venous pressure measured with a balloon catheter.用球囊导管测量肝静脉楔压和自由肝静脉压。
Gastroenterology. 1979 Feb;76(2):253-8.