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幽门和胃窦在犬类液体及可消化固体胃排空中的单独及联合作用。

Individual and combined roles of the pylorus and the antrum in the canine gastric emptying of a liquid and a digestible solid.

作者信息

Hinder R A

出版信息

Gastroenterology. 1983 Feb;84(2):281-6.

PMID:6848407
Abstract

The gastric emptying of a liquid (5% dextrose) and a digestible solid (liver) were studied in 8 dogs with an intact stomach, after pylorectomy, after antrectomy, and after distal (Billroth I) gastrectomy. Pylorectomy and particularly Billroth I gastrectomy resulted in more rapid gastric emptying of the liquid. With an intact stomach, the digestible solid was broken down predominantly (93.8%) into very small particle size (less than 0.15 mm) before being passed into the duodenum. This ability was largely preserved after both pylorectomy or antrectomy. Billroth I gastrectomy resulted in the small bowel being presented with much larger particles of a digestible solid than if the antrum or the pylorus, or both, were preserved. After excision of both the antrum and the pylorus, 38.2% of the liver emptied in particle size greater than 1 mm as opposed to 2.5% from the intact stomach, 4.9% after pylorectomy, and 6.1% after antrectomy. Thus, both the pylorus and the antrum can control the gastric emptying of both a liquid and a digestible solid.

摘要

对8只胃完整、行幽门切除术后、行胃窦切除术后以及行远端(毕罗Ⅰ式)胃切除术后的犬,研究了液体(5%葡萄糖)和可消化固体(肝脏)的胃排空情况。幽门切除术,尤其是毕罗Ⅰ式胃切除术导致液体的胃排空更快。胃完整时,可消化固体在进入十二指肠之前,主要(93.8%)分解为非常小的颗粒大小(小于0.15毫米)。幽门切除术或胃窦切除术后,这种能力在很大程度上得以保留。与保留胃窦或幽门或两者相比,毕罗Ⅰ式胃切除术导致小肠接收的可消化固体颗粒要大得多。切除胃窦和幽门后,38.2%的肝脏以大于1毫米的颗粒大小排空,而胃完整时为2.5%,幽门切除术后为4.9%,胃窦切除术后为6.1%。因此幽门和胃窦均可控制液体和可消化固体的胃排空。

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