Durbec J P, Chevillotte G, Bidart J M, Berthezene P, Sarles H
Br J Cancer. 1983 Apr;47(4):463-70. doi: 10.1038/bjc.1983.75.
In view of the increased incidence of pancreatic cancer and the possible aetiological role of certain dietary factors, a retrospective epidemiological study was undertaken to investigate the roles of tobacco, alcohol, fat, protein and carbohydrate intakes. Sixty-nine patients with pancreatic adenocarcinoma, and 199 normal subjects were interviewed. Data were obtained on life time drinking, smoking and dietary habits. Conditional logistic regression models were used to analyse the relative risk variations. It was shown that the relative risk of cancer of the pancreas increases with fat and alcohol intakes, does not vary with protein intake, and decreases with carbohydrate intake and duration of alcohol consumption. Alcohol may be not directly involved in the aetiology of cancer of the pancreas: its effect could be due to the contents of some alcoholic beverages.
鉴于胰腺癌发病率上升以及某些饮食因素可能的病因学作用，开展了一项回顾性流行病学研究，以调查烟草、酒精、脂肪、蛋白质和碳水化合物摄入量的作用。对69例胰腺腺癌患者和199名正常受试者进行了访谈。获取了关于终生饮酒、吸烟和饮食习惯的数据。使用条件逻辑回归模型分析相对风险变化。结果表明，胰腺癌的相对风险随脂肪和酒精摄入量增加而增加，随蛋白质摄入量无变化，随碳水化合物摄入量和饮酒时间减少而降低。酒精可能并非直接参与胰腺癌的病因学：其作用可能归因于某些酒精饮料的成分。
