Levin D L, Connelly R R, Devesa S S
Cancer. 1981 Mar 15;47(6 Suppl):1456-68. doi: 10.1002/1097-0142(19810315)47:6+<1456::aid-cncr2820471404>3.0.co;2-6.
Mortality and incidence rates for pancreatic cancer in the United States were examined by various demographic characteristics. Disease rates have continued to increase over time but at a much slower pace than in earlier years. Most recently available rates for blacks were significantly higher than for whites and rates for males of each race were higher than for females. Income and education levels had little influence on incidence rates among either blacks or whites. Incidence rates were not significantly higher in urban as compared with rural areas of Iowa and Colorado. The two-year survival rate for pancreatic cancer was about 5% in recent years and did not vary significantly by race or sex. Smoking and diabetes, the two risk factors most consistently associated with the pancreatic cancer, explain only a small proportion of the disease. Much epidemiologic work remains to be done.
研究人员依据不同人口统计学特征,对美国胰腺癌的死亡率和发病率进行了考察。随着时间推移,发病率持续上升,但增速远低于前些年。最新数据显示,黑人的发病率显著高于白人,且每个种族男性的发病率均高于女性。收入和教育水平对黑人和白人的发病率影响甚微。在爱荷华州和科罗拉多州,城市地区的发病率与农村地区相比并无显著差异。近年来,胰腺癌的两年生存率约为5%,在种族和性别方面并无显著差异。吸烟和糖尿病是与胰腺癌关联最为密切的两个风险因素,但它们仅能解释一小部分病例。仍有大量流行病学工作有待开展。