De Vos V
Vet Rec. 1978 Jul 22;103(4):64-8. doi: 10.1136/vr.103.4.64.
Field trials were conducted with the potent morphine-like analgesic, R33799 (Janssen Pharmaceutica; Beerse, Belgium) in South African national parks on 217 free-ranging wild animals, representing 20 different species. The drug was found to be effective and safe for a wide range of ungulates and pachyderms and Burchell's zebra (Equus burchelli) did not react to expected dosage levels. A suggested dosage regime for 19 species is given. Recommended optimal dosage rates varies from about 1 microgram per kg for pachyderms to about 10 microgram per kg for most of the larger ungulates. Xylazine and azaperone were found valuable adjuncts to R33799 in dosage ratios of 10:1 and 30:1 respectively.
在南非国家公园对217只自由放养的野生动物（分属20个不同物种）进行了强效类吗啡镇痛剂R33799（杨森制药公司，比利时贝尔瑟）的野外试验。结果发现，该药物对多种有蹄类动物和厚皮类动物有效且安全，而布氏斑马（Equus burchelli）对预期剂量水平无反应。给出了19个物种的建议给药方案。推荐的最佳剂量率各不相同，厚皮类动物约为每千克1微克，大多数大型有蹄类动物约为每千克10微克。已发现赛拉嗪和阿扎哌隆分别按10:1和30:1的剂量比作为R33799的有效辅助药物。
