Koepsell T D
Comput Biomed Res. 1983 Apr;16(2):136-43. doi: 10.1016/0010-4809(83)90014-9.
Stratification of study subjects by one or more covariates is a commonly accepted method for dealing with confounding and effect modification in epidemiologic case-control studies. A flexible FORTRAN program is described which facilitates simultaneous stratification by several covariates and which produces summary odds ratio estimates and chi-square statistics by the Mantel-Haenszel method. It also facilitates detection of effect modification by each covariate considered individually. Straightforward means are provided for the user to modify input data before analysis or to exclude certain subjects from analysis, simulating such capabilities in larger statistical packages.
通过一个或多个协变量对研究对象进行分层是流行病学病例对照研究中处理混杂和效应修饰的一种普遍接受的方法。本文描述了一个灵活的FORTRAN程序,该程序便于通过多个协变量进行同时分层,并通过Mantel-Haenszel方法生成汇总比值比估计值和卡方统计量。它还便于单独检测每个协变量的效应修饰。为用户提供了直接的方法,以便在分析前修改输入数据或从分析中排除某些对象,从而模拟大型统计软件包中的此类功能。