Plancarte A, Flisser A, Larralde C
Cytobios. 1983;36(142):83-93.
The most prominent antigen of the cysticercus of Taenia solium in the serology of human cysticercosis, antigen B, is capable of agglutinating red blood cells of different species, of aligning in vitro cell growth of transformed mouse fibroblasts, and of strongly binding to pig, rat and human collagen. Scatchard analysis of the adsorption isotherms indicates quite avid heterogeneous binding of antigen B to rat collagen (K's = 10(3), 10(5)). These remarkable biological activities of antigen B, resembling those of fibronectins, allow for some speculation concerning its role in the host-parasite relationship (i.e. organizing vicinal host components to improve the parasite's lodging niche; the 'smoke screen' effect for the host's immune response; Clq inhibition), and expand fibronectin-like properties to molecules from Phyla other than vertebrates.
在人体囊尾蚴病血清学中，猪带绦虫囊尾蚴最突出的抗原——抗原B，能够凝集不同物种的红细胞，能在体外使转化的小鼠成纤维细胞排列生长，还能与猪、大鼠和人类的胶原蛋白强烈结合。对抗吸附等温线进行斯卡查德分析表明，抗原B与大鼠胶原蛋白有相当强烈的异质结合（结合常数K分别为10³、10⁵）。抗原B这些显著的生物学活性与纤连蛋白的活性相似，这使得人们可以对其在宿主 - 寄生虫关系中的作用进行一些推测（即组织邻近的宿主成分以改善寄生虫的寄居环境；对宿主免疫反应的“烟幕”效应；补体C1q抑制），并将纤连蛋白样特性扩展到脊椎动物以外的其他门的分子。
