Ostensen M, Aune B, Husby G
Scand J Rheumatol. 1983;12(2):69-72. doi: 10.3109/03009748309102886.
The effect of pregnancy on the activity of rheumatoid arthritis (RA) was evaluated in 31 patients who had given birth to 49 infants after the onset of their disease. Pregnancy-associated remission of RA was experienced by 75% of the patients. On the other hand, disease exacerbation after delivery occurred in 62% of them. RA had no harmful effect on pregnancy or on the fetus. Hormonal changes during the menstrual cycle or during the use of hormonal contraceptives did not seem to influence the symptoms of RA. Factors possibly involved in remission of RA during pregnancy are discussed.
对31例在疾病发作后生育了49名婴儿的患者进行了妊娠对类风湿关节炎（RA）活动影响的评估。75%的患者经历了与妊娠相关的RA缓解。另一方面，62%的患者在分娩后病情加重。RA对妊娠或胎儿没有有害影响。月经周期或使用激素避孕药期间的激素变化似乎不会影响RA的症状。文中讨论了妊娠期间可能与RA缓解有关的因素。
