慢性气道阻塞患者的血乳酸与呼吸肌疲劳
Blood lactate and respiratory muscle fatigue in patients with chronic airways obstruction.
作者信息
Cooke N T, Wilson S H, Freedman S
出版信息
Thorax. 1983 Mar;38(3):184-7. doi: 10.1136/thx.38.3.184.
Blood lactate concentrations were measured in five patients with chronic airways obstruction after 10 minutes' sustained maximal voluntary ventilation (SMVV) with end-tidal carbon dioxide tension kept constant and after a 12-minute walk. No patient showed a significant rise in blood lactate after SMVV but all showed evidence of low-frequency fatigue of the sternomastoid muscle. After a 12-minute walk three patients showed a significant rise in blood lactate and two of them also had evidence of low-frequency fatigue of the sternomastoid muscle. The absence of a rise in blood lactate after SMVV may be due to the fact that in patients with chronic airways obstruction ventilation is limited by airflow obstruction to a level where only a small muscle mass is used, or where the aerobic capacity of the respiratory muscles is not exceeded.
对5例慢性气道阻塞患者进行了如下研究：在持续最大自主通气（SMVV）10分钟且终末潮气二氧化碳分压保持恒定后，以及在步行12分钟后，测量其血乳酸浓度。在进行SMVV后，没有患者的血乳酸显著升高，但所有患者均显示胸锁乳突肌存在低频疲劳迹象。步行12分钟后，3例患者血乳酸显著升高，其中2例患者胸锁乳突肌也有低频疲劳迹象。SMVV后血乳酸未升高，可能是由于慢性气道阻塞患者的通气受气流阻塞限制，仅使用了少量肌肉，或者呼吸肌的有氧能力未被超过。
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