呼吸肌产生乳酸。
Production of lactic acid by respiratory muscles.
作者信息
Freedman S, Cooke N T, Moxham J
出版信息
Thorax. 1983 Jan;38(1):50-4. doi: 10.1136/thx.38.1.50.
Abstract
We measured blood lactate in normal subjects after 10 minutes of sustained maximum voluntary ventilation (SMVV) with end-tidal Pco kept constant and after breathing against a big added respiratory load for 200 breaths. With SMVV subjects sustained on average 68% of the predicted maximum breathing capacity and achieved final lactate concentrations of 1·9 mmol/l (17·1 mg/100 ml), representing an average increase of about 1·0 mmol/l (9·0 mg/100 ml) over resting values. There was a wide range between individuals, from no increase at all to 2·7 mmol/l, despite similar levels of ventilation. Breathing against added loads produced much smaller changes in blood lactate.
摘要
我们在潮末二氧化碳分压保持恒定的情况下，对正常受试者进行10分钟持续最大自主通气（SMVV）后，以及在对抗大的附加呼吸负荷呼吸200次后，测量了血乳酸水平。在进行SMVV时，受试者平均维持在预测最大呼吸能力的68%，最终血乳酸浓度达到1.9毫摩尔/升（17.1毫克/100毫升），相较于静息值平均升高约1.0毫摩尔/升（9.0毫克/100毫升）。尽管通气水平相似，但个体之间的差异很大，从完全没有升高到2.7毫摩尔/升。对抗附加负荷呼吸时，血乳酸的变化要小得多。
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