Breitwieser W R, Hartman C W, Morris W S, Fleetwood M K, Baxter J A, Albertini R E
Thorax. 1983 Mar;38(3):209-11. doi: 10.1136/thx.38.3.209.
To assess the diagnostic value of measuring free plasma deoxyribonucleic acid (DNA) in patients suspected of having pulmonary embolism, we prospectively assayed the plasma of 40 consecutive patients who underwent pulmonary angiography for the presence of free plasma DNA. Fifteen of them had angiographic evidence of pulmonary embolism. Of these 15 only two (13%) had a positive result in the test for free double-stranded plasma DNA. We concluded that measuring free double-stranded plasma DNA is of no value in the diagnosis of pulmonary embolism.
为评估测量游离血浆脱氧核糖核酸（DNA）对疑似肺栓塞患者的诊断价值，我们前瞻性地检测了40例连续接受肺血管造影的患者血浆中游离血浆DNA的存在情况。其中15例有肺栓塞的血管造影证据。在这15例中，只有2例（13%）游离双链血浆DNA检测结果为阳性。我们得出结论，测量游离双链血浆DNA对肺栓塞的诊断没有价值。
