Hemmingsson E, Sténson S
Acta Obstet Gynecol Scand. 1983;62(1):39-42. doi: 10.3109/00016348309155756.
A review is given of results from a 3-5-year follow-up of 105 young women treated with cryosurgery for a histopathologically verified dysplasia or carcinoma in situ of the uterine cervix. The recovery rate was 88%, with a slightly higher figure in the dysplasia group compared with that of carcinoma in situ. No invasive carcinoma was diagnosed and cases of treatment failure, all diagnosed within one year after cryosurgery, did not develop into a more severe form of neoplasia than previously. No recurrence has been noted so far and very few complications have been recorded. It is concluded that cryosurgery is an easy and effective method of treating cervical intra-epithelial neoplasia in young women. We stress, however, the importance of correct histopathological diagnosis prior to therapy and that after treatment the status of the patient must be checked with vaginal smears over a long period of time.
对105名接受冷冻手术治疗的年轻女性进行了3至5年的随访，这些女性经组织病理学证实患有子宫颈发育异常或原位癌。治愈率为88%，发育异常组的治愈率略高于原位癌组。未诊断出浸润性癌，所有治疗失败病例均在冷冻手术后一年内确诊，且未发展为比之前更严重的肿瘤形式。目前尚未发现复发情况，记录的并发症也很少。结论是，冷冻手术是治疗年轻女性宫颈上皮内瘤变的一种简便有效的方法。然而，我们强调治疗前正确组织病理学诊断的重要性，以及治疗后必须长期通过阴道涂片检查患者的状况。
