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[十六十八醇(Lanette O)接触性过敏作为淤积性皮炎和腿部溃疡治疗中的一个问题]

[Contact allergy to cetylstearylalcohol (Lanette O) as a therapeutic problem in stasis dermatitis and leg ulcer].

作者信息

Keilig W

出版信息

Derm Beruf Umwelt. 1983;31(2):50-4.

PMID:6861645
Abstract

Contact allergic investigations in 2064 patch tested patients (1977-1981) showed that 3,9% had a contact allergy from cetylstearylalcohol (Lanette O). 453 of these patients suffered from stasis dermatitis and leg ulcer. 15% of these 453 patients had a contact allergy from Lanette O, whereas 85% of all patients with Lanette allergy suffered from stasis dermatitis with and without leg ulcers. A closer association between this contact-allergy and these diseases is therefore indicated. Further problems arise due to the presence of cetylstearylalcohol in numerous topical preparations (examples are given) and the often incomplete declaration of the bases and ingredients.

摘要

对2064例进行斑贴试验的患者(1977 - 1981年)进行的接触性过敏调查显示,3.9%的患者对鲸蜡硬脂醇(Lanette O)存在接触性过敏。这些患者中有453例患有淤积性皮炎和腿部溃疡。在这453例患者中,15%对Lanette O存在接触性过敏,而所有对Lanette过敏的患者中,85%患有伴有或不伴有腿部溃疡的淤积性皮炎。因此,表明这种接触性过敏与这些疾病之间存在更密切的关联。由于鲸蜡硬脂醇存在于众多外用制剂中(给出了示例),且基质和成分的标注往往不完整,从而引发了更多问题。

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