麻醉诱导时静脉注射格隆溴铵与阿托品的比较
Intravenous glycopyrrolate and atropine at induction of anaesthesia: a comparison.
作者信息
Greenan J, Dewar M, Jones C J
出版信息
J R Soc Med. 1983 May;76(5):369-71. doi: 10.1177/014107688307600508.
Abstract
In unpremedicated patients presenting for general anaesthesia for electroconvulsive therapy (ECT), the use of atropine combined with methohexitone as an intravenous induction agent was found to produce a significantly greater increase in heart rate than glycopyrrolate in similar combination. There was no difference in the antisialogogue effect of the two drugs at the doses used, and both drugs provided similar protection against the effects of suxamethonium and ECT on heart rate.
摘要
在未接受术前用药、拟接受电休克治疗（ECT）全身麻醉的患者中，发现将阿托品与美索比妥作为静脉诱导剂联合使用时，其导致的心率增加幅度显著大于类似联合使用格隆溴铵时。在所使用的剂量下，两种药物的抗唾液分泌作用没有差异，且两种药物对琥珀胆碱和ECT对心率的影响均提供了相似的保护作用。
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本文引用的文献
1
Effect of suxamethonium on cardiac rhythm.琥珀酰胆碱对心律的影响。
Br Med J. 1960 Dec 17;2(5215):1774-7. doi: 10.1136/bmj.2.5215.1774.
2
Effects of intravenous administration of glycopyrrolate and atropine in anaesthetised patients.静脉注射格隆溴铵和阿托品对麻醉患者的影响。
Anaesthesia. 1981 Mar;36(3):277-81. doi: 10.1111/j.1365-2044.1981.tb10200.x.
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Cardiovascular effects of short-term anaesthesia with methohexitone and propanidid in normal subjects.
Br J Anaesth. 1972 Jan;44(1):2-7. doi: 10.1093/bja/44.1.2-a.
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Atropine and glycopyrronium premedication. A comparison of the effects on cardiac rate and rhythm during induction of anaesthesia.阿托品与格隆溴铵的术前用药。麻醉诱导期间对心率和心律影响的比较。
Anaesthesia. 1978 Nov-Dec;33(10):906-12.
5
Anticholinergic drugs in anaesthesia. A survey of their present position.麻醉中的抗胆碱能药物。对其当前状况的调查。
Anaesthesia. 1978 Feb;33(2):133-8. doi: 10.1111/j.1365-2044.1978.tb08340.x.
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Evaluation of the anticholinergic actions of glycopyrronium bromide.格隆溴铵抗胆碱能作用的评估。
Br J Clin Pharmacol. 1978 Jan;5(1):77-84. doi: 10.1111/j.1365-2125.1978.tb01601.x.
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Glycopyrrolate as a premedicant: comparison with atropine.格隆溴铵作为术前用药：与阿托品的比较。
Br J Anaesth. 1979 Sep;51(9):885-9. doi: 10.1093/bja/51.9.885.
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