Schwartz A, Vignola P A, Walker H J, King M E, Goldblatt A
Ann Intern Med. 1978 Sep;89(3):329-35. doi: 10.7326/0003-4819-89-3-329.
Fifty-five consecutive patients with aortic stenosis underwent echocardiography at the time of cardiac catheterization. Left ventricular systolic pressure was estimated from the echocardiogram assuming that peak systolic circumferential was stress was constant. Systolic blood pressure was substracted from the estimated left ventricular pressure to obtain the aortic-valve gradient. Of 44 patients with adequate echocardiograms and catheterization studies, 30 had their aortic gradient accurately estimated by the echocardiogram (r = 0.75). All 30 patients had normal left ventricular systolic function estimated echocardiographically. The echocardiogram underestimated the aortic gradient in all seven patients with poor left ventricular systolic function. An accurate echocardiographic estimate of aortic-valve gradient can be obtained in patients with normal left ventricular function. The technique can identify those patients with insignificant left ventricular outflow obstruction, thereby obviating the need for invasive studies.
55例连续性主动脉瓣狭窄患者在心脏导管检查时接受了超声心动图检查。假设收缩期圆周应力恒定，从超声心动图估算左心室收缩压。从估算的左心室压力中减去收缩压以获得主动脉瓣压差。在44例有足够超声心动图和导管检查结果的患者中，30例的主动脉压差通过超声心动图得到准确估算（r = 0.75）。所有30例患者经超声心动图估算左心室收缩功能均正常。在所有7例左心室收缩功能差的患者中，超声心动图均低估了主动脉压差。对于左心室功能正常的患者，可通过超声心动图准确估算主动脉瓣压差。该技术可识别那些左心室流出道梗阻不明显的患者，从而无需进行侵入性检查。
