Hernández L L, Powell D A
Peptides. 1983 Jan-Feb;4(1):37-41. doi: 10.1016/0196-9781(83)90162-6.
Albino rabbits were subjected to Pavlovian (classical) conditioning and extinction of concomitant heart rate and eyeblink responses. Sixty minutes before each of three extinction sessions animals were treated with 5 or 20 micrograms/kg of deamino-dicarba-arginine-8-vasopressin or saline. Vasopressin treatment delayed extinction of bradycardiac conditioned responses but did not affect concomitant eyeblink conditioned responses. It was concluded that classically conditioned autonomic responses may be useful tools for studying the effects of peptides on learning.
将白化兔进行巴甫洛夫(经典)条件反射实验,并对伴随的心率和眨眼反应进行消退实验。在三次消退实验的每一次实验前60分钟,给动物注射5或20微克/千克的脱氨基二碳精氨酸-8-加压素或生理盐水。加压素治疗延迟了心动过缓条件反应的消退,但不影响伴随的眨眼条件反应。得出的结论是,经典条件反射的自主反应可能是研究肽对学习影响的有用工具。