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口服沙丁胺醇和茶碱对学龄前哮喘儿童的疗效。

Efficacy of orally administered salbutamol and theophylline in pre-schoolchildren with asthma.

作者信息

Groggins R C, Lenney W, Milner A D, Stokes G M

出版信息

Arch Dis Child. 1980 Mar;55(3):204-6. doi: 10.1136/adc.55.3.204.

DOI:10.1136/adc.55.3.204
PMID:6992715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1626748/
Abstract

Oral administration of salbutamol and theophylline has been shown to be effective in relieving bronchoconstriction in asthmatic children aged between 3 and 5 years. Changes in respiratory function were monitored using a Wright's low range peak flow meter and a modification of the forced oscillation technique. A combination of both drugs in half doses was as effective as either alone. Nebulised salbutamol produced considerable further improvement in lung function.

摘要

已证明口服沙丁胺醇和茶碱对缓解3至5岁哮喘儿童的支气管收缩有效。使用赖特氏低量程峰值流量计和改良的强迫振荡技术监测呼吸功能的变化。两种药物半量联合使用与单独使用任一药物的效果相同。雾化沙丁胺醇可使肺功能得到进一步显著改善。

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本文引用的文献

1
Peak expiratory flow rates in children under 5 years of age.5岁以下儿童的呼气峰值流速
Arch Dis Child. 1970 Dec;45(244):780-2. doi: 10.1136/adc.45.244.780.
2
Prevalence, natural history, and relationship of wheezy bronchitis and asthma in children. An epidemiological study.儿童喘息性支气管炎和哮喘的患病率、自然病史及关系:一项流行病学研究
Br Med J. 1969 Nov 8;4(5679):321-5. doi: 10.1136/bmj.4.5679.321.
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Forced oscillation technique for determination of resistance to breathing in children.用于测定儿童呼吸阻力的强迫振荡技术
Arch Dis Child. 1973 Apr;48(4):259-66. doi: 10.1136/adc.48.4.259.
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At what age do bronchodilator drugs work?支气管扩张剂药物在什么年龄起作用?
Arch Dis Child. 1978 Jul;53(7):532-5. doi: 10.1136/adc.53.7.532.
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Recurrent wheezing in the preschool child.学龄前儿童反复喘息
Arch Dis Child. 1978 Jun;53(6):468-73. doi: 10.1136/adc.53.6.468.
6
Continuous and intermittent salbutamol tablet administration in asthmatic children.哮喘儿童持续和间歇服用沙丁胺醇片
Br J Dis Chest. 1979 Jul;73(3):277-81.
7
Comparison of cromoglycate (cromolyn) and theophylline in controlling symptoms of chronic asthma. A collaborative study.
Lancet. 1977 Feb 19;1(8008):381-5. doi: 10.1016/s0140-6736(77)92601-0.