Fernández V, Fernández N, Valenzuela A, Videla L A
Experientia. 1983 Aug 15;39(8):880-2. doi: 10.1007/BF01990416.
Acute ethanol treatment of rats (5 g/kg) has a biphasic effect on the glutathione content of the erythrocyte. After 3 h of intoxication there is a diminution in total GSH equivalents, followed by a recovery to basal values 6 h after treatment. The decrease of total GSH equivalents is mainly due to a diminution of the oxidized form of the tripeptide. Concomitantly a marked increase in the plasma level of glutathione was found at 3 h, followed by a diminution to values obtained at time zero.
用乙醇（5克/千克）对大鼠进行急性处理，会对红细胞中的谷胱甘肽含量产生双相效应。中毒3小时后，总谷胱甘肽当量减少，随后在处理6小时后恢复至基础值。总谷胱甘肽当量的减少主要是由于三肽氧化形式的减少。与此同时，在3小时时发现血浆中谷胱甘肽水平显著升高，随后降至处理前（零时）的水平。
