Strupler W
Int J Pediatr Otorhinolaryngol. 1983 Apr;5(2):213-6. doi: 10.1016/s0165-5876(83)80027-5.
A rare case of a papillary thyroid cancer in a young boy is reported. At the age of 8 years a rapidly growing tumour of the right antero-lateral neck region was detected. Biopsy revealed a cervical lymph node metastasis of a papillary thyroid carcinoma. Any adequate therapy was rejected by the patient's father. After two years of delay, at the age of ten, a severe dyspnoea urged to an emergency tracheotomy. The further investigations revealed a bilateral partly papillary, partly follicular and partly anaplastic thyroid carcinoma with infiltration and compression of the cervical trachea and the cricoid and with right recurrent nerve paralysis. The thyroid cancer was classified as T3N2bM0. To save the boy's life an extensive operation was performed with total extirpation of the thyroid gland and the adjacent tissues, total laryngectomy and resection of the cervical trachea, combined with bilateral neck dissection. The patient has been given no other treatment than hormone substitution during 16 years after surgery. The patient grew up normally and stayed recurrence-free. As far as we could find in world literature, this is the youngest patient with total laryngectomy, partial resection of the trachea, total thyroidectomy and bilateral neck dissection.
报告了一例年轻男孩患乳头状甲状腺癌的罕见病例。8岁时，发现右侧颈前外侧区域有一个迅速生长的肿瘤。活检显示为乳头状甲状腺癌的颈部淋巴结转移。患者父亲拒绝了任何适当的治疗。延误两年后，10岁时，严重的呼吸困难促使进行了紧急气管切开术。进一步检查发现双侧部分为乳头状、部分为滤泡状且部分为间变性甲状腺癌，侵犯并压迫颈段气管和环状软骨，右侧喉返神经麻痹。甲状腺癌被分类为T3N2bM0。为挽救男孩的生命，进行了广泛的手术，包括甲状腺及相邻组织的全切除、全喉切除术和颈段气管切除术，并结合双侧颈部淋巴结清扫术。术后16年期间，患者除了接受激素替代治疗外未接受其他治疗。患者正常成长，未出现复发。据我们在世界文献中所能查到的，这是接受全喉切除术、部分气管切除术、全甲状腺切除术和双侧颈部淋巴结清扫术的最年轻患者。
