强直性肌营养不良患者握力、肌强直及疲劳的定量检测

Quantitative testing of handgrip strength, myotonia, and fatigue in myotonic dystrophy.

作者信息

Torres C, Moxley R T, Griggs R C

出版信息

J Neurol Sci. 1983 Jul;60(1):157-68. doi: 10.1016/0022-510x(83)90135-1.

Abstract

An electrically calibrated, isometric hand dynamometer was used to quantitate maximum voluntary contraction (MVC(, relaxation time and fatigue time (at 50% MVC) in 18 normal and 10 myotonic dystrophy subjects. Precise measurements of MVC and fatigue time were obtained in normals and myotonic dystrophy patients. Relaxation times were markedly prolonged and were quite variable in all patients with myotonic dystrophy in contrast to the highly reproducible times in normals. Neither "warm-up" activity nor acetazolamide treatment altered relaxation time.

摘要

使用一台经过电校准的等长握力计，对18名正常人和10名强直性肌营养不良患者的最大自主收缩（MVC）、放松时间和疲劳时间（50%MVC时）进行定量分析。在正常人和强直性肌营养不良患者中均获得了MVC和疲劳时间的精确测量值。与正常人高度可重复的放松时间相比，强直性肌营养不良患者的放松时间明显延长且变化很大。“热身”活动和乙酰唑胺治疗均未改变放松时间。