• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

强直性肌营养不良患者握力、肌强直及疲劳的定量检测

Quantitative testing of handgrip strength, myotonia, and fatigue in myotonic dystrophy.

作者信息

Torres C, Moxley R T, Griggs R C

出版信息

J Neurol Sci. 1983 Jul;60(1):157-68. doi: 10.1016/0022-510x(83)90135-1.

DOI:10.1016/0022-510x(83)90135-1
PMID:6875612
Abstract

An electrically calibrated, isometric hand dynamometer was used to quantitate maximum voluntary contraction (MVC(, relaxation time and fatigue time (at 50% MVC) in 18 normal and 10 myotonic dystrophy subjects. Precise measurements of MVC and fatigue time were obtained in normals and myotonic dystrophy patients. Relaxation times were markedly prolonged and were quite variable in all patients with myotonic dystrophy in contrast to the highly reproducible times in normals. Neither "warm-up" activity nor acetazolamide treatment altered relaxation time.

摘要

使用一台经过电校准的等长握力计,对18名正常人和10名强直性肌营养不良患者的最大自主收缩(MVC)、放松时间和疲劳时间(50%MVC时)进行定量分析。在正常人和强直性肌营养不良患者中均获得了MVC和疲劳时间的精确测量值。与正常人高度可重复的放松时间相比,强直性肌营养不良患者的放松时间明显延长且变化很大。“热身”活动和乙酰唑胺治疗均未改变放松时间。

相似文献

1
Quantitative testing of handgrip strength, myotonia, and fatigue in myotonic dystrophy.强直性肌营养不良患者握力、肌强直及疲劳的定量检测
J Neurol Sci. 1983 Jul;60(1):157-68. doi: 10.1016/0022-510x(83)90135-1.
2
Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2.使用市售测力计对 1 型和 2 型肌强直性营养不良进行定量肌强直评估。
Muscle Nerve. 2019 Apr;59(4):431-435. doi: 10.1002/mus.26401. Epub 2019 Jan 9.
3
Computerized hand grip myometry reliably measures myotonia and muscle strength in myotonic dystrophy (DM1).计算机化握力肌测量法能够可靠地测量强直性肌营养不良症(DM1)中的肌强直和肌肉力量。
Muscle Nerve. 2007 Sep;36(3):320-8. doi: 10.1002/mus.20822.
4
The changes in muscle strength and relaxation time after a comprehensive rehabilitation program for patients with myotonic dystrophy.强直性肌营养不良患者综合康复计划后肌肉力量和放松时间的变化。
Yonsei Med J. 1996 Aug;37(4):237-42. doi: 10.3349/ymj.1996.37.4.237.
5
Quantitative analysis of the "warm-up" phenomenon in myotonic dystrophy type 1.1型强直性肌营养不良症“热身”现象的定量分析
Muscle Nerve. 2005 Jul;32(1):35-42. doi: 10.1002/mus.20339.
6
Evoked myotonia can be "dialed-up" by increasing stimulus train length in myotonic dystrophy type 1.肌强直性肌病 1 型可通过增加肌电刺激的串长度来“调高”诱发肌强直。
Muscle Nerve. 2010 Feb;41(2):191-6. doi: 10.1002/mus.21481.
7
Myotonic dystrophy: quantification of muscle weakness and myotonia and the effect of amitriptyline and exercise.
Arch Phys Med Rehabil. 1990 Nov;71(12):983-7.
8
A study of repeated lateral pinch grip in myotonic dystrophy.强直性肌营养不良患者反复进行侧捏握力的研究。
Physiother Res Int. 1999;4(1):1-11. doi: 10.1002/pri.1999.4.1.1.
9
Physiological characterisation of the "warm up" effect of activity in patients with myotonic dystrophy.强直性肌营养不良患者活动“热身”效应的生理学特征
J Neurol Neurosurg Psychiatry. 1988 Sep;51(9):1134-41. doi: 10.1136/jnnp.51.9.1134.
10
Effect of acetazolamide on insulin sensitivity in myotonic disorders.乙酰唑胺对强直性肌营养不良症患者胰岛素敏感性的影响。
Arch Neurol. 1984 Jul;41(7):740-3. doi: 10.1001/archneur.1984.04050180062019.

引用本文的文献

1
Open-source, MRI-compatible grip force sensor for dynamic muscle imaging.用于动态肌肉成像的开源、磁共振成像兼容握力传感器。
MAGMA. 2025 Jul 25. doi: 10.1007/s10334-025-01282-y.
2
Muscle Ultrasound Shear Wave Elastography as a Non-Invasive Biomarker in Myotonia.肌肉超声剪切波弹性成像作为强直性肌营养不良的一种非侵入性生物标志物
Diagnostics (Basel). 2021 Jan 23;11(2):163. doi: 10.3390/diagnostics11020163.
3
Antisense oligonucleotide and adjuvant exercise therapy reverse fatigue in old mice with myotonic dystrophy.反义寡核苷酸与辅助运动疗法可逆转患强直性肌营养不良的老年小鼠的疲劳。
Mol Ther Nucleic Acids. 2020 Nov 26;23:393-405. doi: 10.1016/j.omtn.2020.11.014. eCollection 2021 Mar 5.
4
What is known about the effects of exercise or training to reduce skeletal muscle impairments of patients with myotonic dystrophy type 1? A scoping review.关于运动或训练对1型强直性肌营养不良患者骨骼肌损伤的影响,我们了解多少?一项范围综述。
BMC Musculoskelet Disord. 2019 Mar 5;20(1):101. doi: 10.1186/s12891-019-2458-7.
5
Relationships between grip strength, myotonia, and CTG expansion in myotonic dystrophy type 1.1型强直性肌营养不良症中握力、肌强直与CTG重复序列扩增之间的关系
Ann Clin Transl Neurol. 2017 Nov 7;4(12):921-925. doi: 10.1002/acn3.496. eCollection 2017 Dec.
6
Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel.强直性肌营养不良相关的肌肉无力与剪接失调和钙通道 Ca(V)1.1 门控改变有关。
Hum Mol Genet. 2012 Mar 15;21(6):1312-24. doi: 10.1093/hmg/ddr568. Epub 2011 Dec 2.
7
Endurance time is joint-specific: a modelling and meta-analysis investigation.持续时间具有关节特异性:一项建模和荟萃分析研究。
Ergonomics. 2010 Jan;53(1):109-29. doi: 10.1080/00140130903389068.
8
The non-dystrophic myotonias: molecular pathogenesis, diagnosis and treatment.非营养不良性肌强直症:分子发病机制、诊断与治疗。
Brain. 2010 Jan;133(Pt 1):9-22. doi: 10.1093/brain/awp294. Epub 2009 Nov 16.
9
Clinical evaluation of membrane excitability in muscle channel disorders: potential applications in clinical trials.肌肉通道疾病中膜兴奋性的临床评估:在临床试验中的潜在应用
Neurotherapeutics. 2007 Apr;4(2):205-15. doi: 10.1016/j.nurt.2007.01.011.
10
Nifedipine in the treatment of myotonia in myotonic dystrophy.硝苯地平治疗强直性肌营养不良症的肌强直
J Neurol Neurosurg Psychiatry. 1987 Feb;50(2):199-206. doi: 10.1136/jnnp.50.2.199.