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肺泡蛋白沉积症:10年期间的诊断与治疗

Alveolar proteinosis: diagnosis and treatment over a 10-year period.

作者信息

Du Bois R M, McAllister W A, Branthwaite M A

出版信息

Thorax. 1983 May;38(5):360-3. doi: 10.1136/thx.38.5.360.

Abstract

Ten years' experience of using bronchoalveolar lavage in the treatment of 10 patients with alveolar proteinosis is reported. The diagnosis was often missed. The interval between onset of symptoms and diagnosis varied from six weeks to six years (median 2 years), so that the start of treatment was often delayed. Some patients experienced severe progressive disability before they had treatment. Whole-lung lavage proved to be a safe, repeatable procedure which provided symptomatic, physiological, and radiological improvement and allowed all 10 patients treated to return to full-time employment.

摘要

报告了使用支气管肺泡灌洗术治疗10例肺泡蛋白沉积症患者的十年经验。诊断常常被漏诊。症状出现至诊断的间隔时间从6周至6年不等(中位数为2年),因此治疗常常延迟开始。一些患者在接受治疗前出现了严重的进行性残疾。全肺灌洗术被证明是一种安全、可重复的操作,可带来症状、生理和影像学方面的改善,并使所有接受治疗的10例患者能够恢复全职工作。

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本文引用的文献

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Bronchopulmonary lavage in man.人体支气管肺灌洗
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Pulmonary alveolar proteinosis.肺泡蛋白沉积症
Br J Dis Chest. 1969 Jan;63(1):13-28. doi: 10.1016/s0007-0971(69)80040-9.
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Physiologic effects of bronchopulmonary lavage in alveolar proteinosis.
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