Belcher J R
Thorax. 1983 Jun;38(6):428-32. doi: 10.1136/thx.38.6.428.
A study has been made of 8781 patients with bronchial carcinoma who were operated on by seven surgeons in England during the years 1949-80. There were 3865 pneumonectomies, 3790 lobectomies, and 1126 thoracotomies. During this period the operative mortality has fallen. Neither the resection rate nor the proportion of lobectomies bears any relation to the survival rate in any series. There has been remarkable similarity between the various survival rates in that the difference at five years was only 1.3% (25.5-26.8%) and at 10 years 4.2% (13.6-17.8%). These figures are reflected in reports published worldwide, where there is also great similarity between the results. If the improvement in operative mortality is excluded, there has been no improvement in the survival rates in the last thirty years.
对1949年至1980年间在英国由七位外科医生实施手术的8781例支气管癌患者进行了一项研究。其中有3865例全肺切除术、3790例肺叶切除术和1126例开胸手术。在此期间,手术死亡率有所下降。在任何一组病例中,切除率和肺叶切除术的比例与生存率均无任何关联。不同生存率之间存在显著相似性,五年生存率的差异仅为1.3%(25.5% - 26.8%),十年生存率的差异为4.2%(13.6% - 17.8%)。这些数据在全球发表的报告中都有体现,各地的结果也极为相似。如果排除手术死亡率的改善情况,过去三十年里生存率并无提高。