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芬苯达唑对五种猪寄生虫的疗效。

Efficacy of fenbendazole against five genera of swine parasites.

作者信息

Stewart T B, Marti O G, Hale O M

出版信息

Am J Vet Res. 1981 Jul;42(7):1160-2.

PMID:7271035
Abstract

Thirty-three pigs were sequentially infected with Oesophagostomum spp, Metastrongylus spp, and Trichuris suis while being maintained in lots contaminated with space Ascaris suum, Strongyloides ransomi, and other parasites. Pigs were assigned to 1 of 3 groups on the basis of weight (6.8 to 25.9 kg), sex, and litter. Pigs in the 1st group were used as nontreated controls; pigs in the 2nd and 3rd groups were given fenbendazole in the feed at doses of 3 and 5 mg/kg of body weight, respectively, on 3 successive days. Pigs were necropsied either on the 4th of 5th day after completion of treatment, and worms were recovered and counted. Based on the mean numbers of worms in the control group, drug efficacies at 3 and 5 mg/kg were, respectively, 100% against A suum; 59% and 81% against S ransomi; 97% and 99.9% against Metastrongylus spp; 94% and 99.7% against T suis; and 99.9% against Oesophagostomum spp.

摘要

33头猪在饲养于被猪蛔虫、兰氏类圆线虫和其他寄生虫污染的圈舍中时,依次感染了结节虫属、后圆线虫属和猪鞭虫。根据体重(6.8至25.9千克)、性别和窝别将猪分为3组。第1组猪用作未治疗对照;第2组和第3组猪分别在连续3天的饲料中给予3毫克/千克和5毫克/千克体重剂量的芬苯达唑。在治疗结束后的第4天或第5天对猪进行剖检,回收并计数蠕虫。根据对照组蠕虫的平均数量,3毫克/千克和5毫克/千克剂量的药物疗效分别为:对猪蛔虫100%;对兰氏类圆线虫59%和81%;对后圆线虫属97%和99.9%;对猪鞭虫94%和99.7%;对结节虫属99.9%。

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