肺炎球菌各型之间的沉淀交叉反应。
Precipitating cross-reactions among pneumococcal types.
作者信息
Heidelberger M
出版信息
Infect Immun. 1983 Sep;41(3):1234-44. doi: 10.1128/iai.41.3.1234-1244.1983.
Abstract
Data accumulated over many years are brought together on cross-reactions of 46 among the more than 80 pneumococcal serological types, with the idea of correlating cross-reactions with the structures of the relevant type-specific capsular polysaccharides, insofar as these have been determined. The precipitin reaction was carried out with the polysaccharides and antibodies raised in horses, rabbits, and a mule. Quantitative values (micrograms of antibody nitrogen per milliliter of antiserum at 0 to 1 degree C) are given in many instances and discussed, together with arbitrary qualitative data, in terms of the known structures of the polysaccharides. Some precise relationships are uncovered, and an attempt is made to determine why some of the cross-reactions are reciprocal and why others are only unilateral.
摘要
多年积累的数据被汇总起来，涉及80多种肺炎球菌血清型中的46种的交叉反应，目的是将交叉反应与相关的型特异性荚膜多糖的结构联系起来，只要这些结构已经确定。用多糖以及在马、兔和骡子体内产生的抗体进行沉淀反应。在许多情况下给出了定量值（0至1摄氏度下每毫升抗血清中抗体氮的微克数），并与任意定性数据一起，根据多糖的已知结构进行了讨论。发现了一些精确的关系，并试图确定为什么有些交叉反应是相互的，而有些只是单向的。
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