Solomon D A, Horn B R, Byrd R B, Lorfel R S, Griggs G A
Chest. 1978 Sep;74(3):271-3. doi: 10.1378/chest.74.3.271.
A prospective study of 21 patients with presumed sarcoidosis was performed to determine the value of conjunctival biopsy in diagnosing the disease. Conjunctival lesions were seen in 15 patients on slit-lamp examination, with eight of these showing noncaseating granulomas on biopsy. The abnormalities were seen by the unaided eye in only two cases. All eight biopsies showing noncaseating granulomas occured in the 14 black patients. No clinical, biochemical, or radiographic characteristics identified those patients who would prove to have a biopsy showing such granulomas. This simple, frequently productive procedure may be helpful in the diagnosis of sarcoidosis.
对21例疑似结节病患者进行了一项前瞻性研究，以确定结膜活检在诊断该病中的价值。裂隙灯检查发现15例患者有结膜病变，其中8例活检显示非干酪样肉芽肿。仅2例病变肉眼可见。所有8例显示非干酪样肉芽肿的活检均来自14例黑人患者。没有临床、生化或影像学特征能够识别出活检会显示此类肉芽肿的患者。这种简单且常常有效的检查方法可能有助于结节病的诊断。
