Luft F C, Fineberg N S, Sloan R S
Hypertension. 1982 Jul-Aug;4(4):494-8. doi: 10.1161/01.hyp.4.4.494.
This study was undertaken to formulate reliable confidence limits for the relationship between nocturnal and 24-hour urine sodium (Na) excretion for use in population compliance studies. Urine excretions were measured in 12 white and 12 black men at three levels of sodium (Na) intake (10, 200, and 400 mEq/day) for 7 days. Nocturnal Na, chloride (Cl), and Cl determined by titrator stick were all highly correlated (r greater than or equal to 0.86, p less than 0.001) with 24-hour UNaV. No significant difference could be attributed to race. Discriminate analysis revealed that the subjects could be categorized with respect to Na intake with accuracies of 95%, 90%, and 85% (low, middle, and high Na intake respectively) by means of two nocturnal urine Cl titrator stick measurements. In addition, two such measurements showing nocturnal UClV less than 10 mEq indicated with 95% accuracy that 24-hour UNaV was less than 60 mEq. According to these data, measurement of nocturnal Na or Cl excretion is a useful means of assessing compliance to a low sodium intake, and the titrator sticks are a convenient and inexpensive tool.
本研究旨在为夜间和24小时尿钠（Na）排泄之间的关系制定可靠的置信区间，以用于人群依从性研究。对12名白人男性和12名黑人男性在三种钠（Na）摄入量水平（10、200和400 mEq/天）下进行了7天的尿排泄量测量。夜间Na、氯（Cl）以及通过滴定棒测定的Cl与24小时尿钠排泄量（UNaV）均高度相关（r大于或等于0.86，p小于0.001）。种族之间无显著差异。判别分析显示，通过两次夜间尿Cl滴定棒测量，受试者可根据钠摄入量分别以95%、90%和85%的准确率进行分类（分别为低、中、高钠摄入量）。此外，两次这样的测量显示夜间尿氯排泄量（UClV）小于10 mEq时，有95%的准确率表明24小时UNaV小于60 mEq。根据这些数据，测量夜间Na或Cl排泄是评估低钠摄入依从性的一种有用方法，而滴定棒是一种方便且廉价的工具。
