[有利于巨噬细胞热原产生的条件及其作用机制]
[Conditions favoring production and mechanism of action of macrophage pyrogen].
作者信息
Sorokin A V, Agasarov L G, Efremov O M
出版信息
Biull Eksp Biol Med. 1980 Mar;89(3):278-81.
PMID:6893002
Abstract
Activation of mononuclear phagocytes by staphylococci in vitro results in the production of endogenous pyrogen. Macrophage pyrogen does not posses species pyrogenic specificity. Intracisternal injection increases pyrogen susceptibility more than 100-fold as compared to intravenous injection. Still more abrupt increase in pyrogen susceptibility was observed in the animals in the presence of elevated body cAMP concentration induced by theophylline preinjection.
摘要
体外葡萄球菌激活单核吞噬细胞可导致内源性热原的产生。巨噬细胞热原不具有种属热原特异性。与静脉注射相比，脑池内注射可使热原敏感性增加100倍以上。在预先注射茶碱诱导机体cAMP浓度升高的动物中，观察到热原敏感性的增加更为突然。
相似文献
1
[Conditions favoring production and mechanism of action of macrophage pyrogen].[有利于巨噬细胞热原产生的条件及其作用机制]
Biull Eksp Biol Med. 1980 Mar;89(3):278-81.
2
[Formation of endogenous pyrogen by mononuclear phagocytes].[单核吞噬细胞产生内源性致热原]
Biull Eksp Biol Med. 1980 Mar;89(3):284-6.
3
4
5
6
7
The febrile responses in rabbits and rats to leucocyte pyrogens of different species.家兔和大鼠对不同物种白细胞致热原的发热反应。
J Physiol. 1978 Jun;279:113-20. doi: 10.1113/jphysiol.1978.sp012333.
8
Spontaneous pyrogen production by mouse histiocytic and myelomonocytic tumor cell lines in vitro.小鼠组织细胞和骨髓单核细胞肿瘤细胞系在体外自发产生热原。
J Exp Med. 1978 May 1;147(5):1503-l6.
9
Endogenous pyrogen-like substance produced by reptiles.爬行动物产生的内源性致热原样物质。
J Physiol. 1977 Jun;267(3):659-66. doi: 10.1113/jphysiol.1977.sp011831.
10
Studies on the pathogenesis of fever. XV. The production of endogenous pyrogen by peritoneal macrophages.发热发病机制的研究。十五、腹膜巨噬细胞产生内源性致热原。
J Exp Med. 1967 Aug 1;126(2):385-94. doi: 10.1084/jem.126.2.385.
Zotero 插件