甲状腺功能亢进症患者心脏储备功能的评估。

Assessment of cardiac reserve in patients with hyperthyroidism.

作者信息

Shafer R B, Bianco J A

出版信息

Chest. 1980 Aug;78(2):269-73. doi: 10.1378/chest.78.2.269.

DOI:10.1378/chest.78.2.269

Abstract

Radionuclide multigated cardiac imaging was performed to assess functional cardiac reserve in patients with hyperthyroidism. In 11 normal individuals, submaximl supine exercise increased heart rate (HR) by 60 percent, systolic blood pressure (BP) by 54 percent, and the left ventricular ejection fraction (LVEF) by 13 percent. All of these increments were statistically significant (p < 0.001). Eight patients with hyperthyroidism were studied. Their mean +/- standard error of the mean (SEM) serum thyroxine level was 17.7 +/- 0.5 micrograms percent. There was a negative correlation between serum thyroxine levels and LVEF, both at rest and during exercise, in the patients with hyperthyroidism. Our data suggest that hyperthyroidism is associated with impaired functional cardiac reserve.

摘要

进行放射性核素多门控心脏成像以评估甲状腺功能亢进患者的心脏功能储备。在11名正常个体中，次极量仰卧运动使心率（HR）增加60%，收缩压（BP）增加54%，左心室射血分数（LVEF）增加13%。所有这些增加均具有统计学意义（p<0.001）。对8例甲状腺功能亢进患者进行了研究。他们的血清甲状腺素水平平均±平均标准误差（SEM）为17.7±0.5微克百分比。在甲状腺功能亢进患者中，无论是静息时还是运动时，血清甲状腺素水平与LVEF之间均呈负相关。我们的数据表明，甲状腺功能亢进与心脏功能储备受损有关。