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父系排除与认定:法医遗传学与统计学的实践经验

Exclusions and attributions of paternity: practical experiences of forensic genetics and statistics.

作者信息

Valentin J

出版信息

Am J Hum Genet. 1980 May;32(3):420-31.

PMID:6930157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1686081/
Abstract

The Swedish State Institute for Blood Group Serology is a central government laboratory handling all blood typing in paternity cases in Sweden, each year testing 1,500-2,000 cases using about 13 polymorphisms. Of the accused men, 35%-40% are nonfathers, but in one-man cases (about 78% of all cases), approximately 75% are the true fathers. Exclusions appear to be distributed as expected from allele frequencies, and the paternity probability of nonexcluded men is assessed with a Bayesian approach. Some cases are retested in extended investigations which raise theoretical exclusion capability from about 87% to about 99%. Both the results of extended investigations and the theoretical consideration of the distribution of paternity probabilities support the use of such positive statistical evidence for the attribution of paternity.

摘要

瑞典国家血型血清学研究所是一个中央政府实验室,负责处理瑞典所有亲子鉴定案件中的血型鉴定工作,每年使用约13种多态性检测1500 - 2000个案件。在被指控的男性中,35% - 40%不是孩子的父亲,但在单人案件(约占所有案件的78%)中,约75%是真正的父亲。排除情况似乎按照等位基因频率预期分布,未被排除的男性的父权概率采用贝叶斯方法评估。一些案件在扩展调查中重新检测,这将理论排除能力从约87%提高到约99%。扩展调查的结果以及父权概率分布的理论考量都支持将这种阳性统计证据用于父权归属判定。

相似文献

1
Exclusions and attributions of paternity: practical experiences of forensic genetics and statistics.父系排除与认定:法医遗传学与统计学的实践经验
Am J Hum Genet. 1980 May;32(3):420-31.
2
Expected and observed proportion of subjects excluded from paternity by blood phenotypes of a child and its mother in a sample of 171 families.在171个家庭的样本中,根据孩子及其母亲的血型表型排除父权的预期和观察到的受试者比例。
Am J Hum Genet. 1980 May;32(3):432-44.
3
[Formalisation parental genotype recognition for the computation of probability of paternity (author's transl)].用于计算父权概率的亲代基因型识别形式化(作者译)
Ann Genet. 1981;24(2):93-9.
4
Analysis of paternity. The use of HLA and red cell antigens.
Transfusion. 1984 Jul-Aug;24(4):340-2. doi: 10.1046/j.1537-2995.1984.24484275578.x.
5
Blood groups and genetic markers polymorphism and probability of paternity.血型与遗传标记多态性及父权概率
Transfusion. 1980 Nov-Dec;20(6):684-94. doi: 10.1046/j.1537-2995.1980.20681057158.x.
6
A critical analysis of paternity determination using HLA and five erythrocyte antigen systems.对使用人类白细胞抗原(HLA)和五种红细胞抗原系统进行亲子鉴定的批判性分析。
Am J Forensic Med Pathol. 1983 Mar;4(1):15-23. doi: 10.1097/00000433-198303000-00003.
7
[Use of DNA polymorphism in forensic paternity evaluation].
Z Rechtsmed. 1990;103(4):235-48.
8
The probability of exclusion or likelihood of guilt of an accused: paternity.被告被排除的概率或有罪的可能性:亲子鉴定。
J Forensic Sci Soc. 1983 Jan;23(1):19-25. doi: 10.1016/s0015-7368(83)71538-0.
9
[Genetic methods for the exclusion and attribution of paternity: experience with 30 cases].
Rev Med Chil. 1988 Aug;116(8):736-42.
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[Praxis of the blood group opinion of parentage: systems with low exclusions potency; evidence of serological exclusion; biostatistical problems. Comments to a paper of H. Ritter in FamRZ 1973, 121 (author's transl)].[亲子关系血型鉴定的实践:排除效力低的系统;血清学排除的证据;生物统计学问题。对H. 里特于1973年发表在《家庭法杂志》第121期上一篇论文的评论(作者译)]
Z Rechtsmed. 1975 Sep 5;76(1):49-61. doi: 10.1007/BF02116798.

引用本文的文献

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Fractional paternity assignment: theoretical development and comparison to other methods.亲权指数的分配:理论发展与其他方法的比较。
Theor Appl Genet. 1988 Sep;76(3):369-80. doi: 10.1007/BF00265336.
2
Measuring paternal discrepancy and its public health consequences.测量父系差异及其对公共卫生的影响。
J Epidemiol Community Health. 2005 Sep;59(9):749-54. doi: 10.1136/jech.2005.036517.
3
Evaluating pedigree data. I. The estimation of pedigree error in the presence of marker mistyping.评估系谱数据。I. 存在标记误分型时系谱误差的估计。
Am J Hum Genet. 1983 Mar;35(2):241-62.
4
Some fallacious thinking about the paternity index.一些关于父权指数的错误观念。
Am J Hum Genet. 1986 Apr;38(4):582-9.

本文引用的文献

1
Principles of blood-group statistical evaluation of paternity cases at the University Institute of Forensic Medicine, Copenhagen.哥本哈根大学法医学研究所父权案例血型统计评估原则
Acta Med Leg Soc (Liege). 1956;9(Spec No):83-93.
2
[Does a probability of paternity exist?].[存在父系概率吗?]
Med Leg Dommage Corpor. 1971 Oct-Dec;4(4):348-50.
3
Exclusion of paternity: the current state of the art.父权排除:当前的技术水平
Am J Hum Genet. 1974 Jul;26(4):477-88.
4
[Evaluation of paternity probability determined according to the formula of Eseen-Möller with regard to the given mother-child constellation. Description of the methods; tables and graphs].[根据埃森-默勒公式确定的父权概率对给定母子组合的评估。方法描述;表格和图表]
Dtsch Z Gesamte Gerichtl Med. 1969;66(3):97-122.
5
[Estimation of probability of paternity from blood groups and genetic markers (author's transl)].[根据血型和遗传标记估算父权概率(作者译)]
Nouv Rev Fr Hematol. 1974 Jul-Aug;14(4):477-94.
6
Letter: Probability of paternity: useless.信件:父权概率:毫无用处。
Am J Hum Genet. 1975 Jul;27(4):558-61.
7
Probability of paternity.父权概率
Am J Hum Genet. 1976 Nov;28(6):622-5.
8
Statistical evidence in paternity cases: imperative.亲子鉴定案件中的统计证据:势在必行。
Am J Hum Genet. 1976 Nov;28(6):620-2.
9
A note on the distribution of the number of exclusions to be expected in paternity testing.关于亲子鉴定中预期排除数分布的一则注释。
Am J Hum Genet. 1976 Nov;28(6):615-8.
10
The occurrence of inter-locus disequilibrium in combinations of genetic marker systems in man. A study on material from Swedish paternity cases.人类遗传标记系统组合中基因座间不平衡的发生。对瑞典亲子鉴定案例材料的研究。
Hereditas. 1979;91(2):279-93. doi: 10.1111/j.1601-5223.1979.tb01671.x.