美加明可阻断尼古丁对大鼠下丘脑促性腺激素和促甲状腺激素分泌的抑制作用，以及尼古丁引起的儿茶酚胺周转率的增加。
Mecamylamine induced blockade of nicotine induced inhibition of gonadotrophin and TSH secretion and of nicotine induced increases of catecholamine turnover in the rat hypothalamus.
作者信息
Andersson K, Fuxe K, Eneroth P, Gustafsson J A, Agnati L F
出版信息
Acta Physiol Scand Suppl. 1980;479:27-9.
PMID:6932802
Abstract
Nicotine treatment of normal male rats and of ovariectomized female rats results in increases of dopamine (DA), noradrenaline (NA) and adrenaline (A) turnover in the hypothalamus, especially within the median eminence. These effects may in part mediate the inhibition of gonadotrophin and TSH secretion produced by nicotine.
摘要
对正常雄性大鼠和去卵巢雌性大鼠进行尼古丁处理，会导致下丘脑尤其是正中隆起内的多巴胺（DA）、去甲肾上腺素（NA）和肾上腺素（A）周转率增加。这些效应可能部分介导了尼古丁对促性腺激素和促甲状腺激素分泌的抑制作用。
Zotero 插件