糖尿病患者脑脊液中的山梨醇和肌醇水平。
Sorbitol and myoinositol levels in the cerebrospinal fluid of diabetic patients.
作者信息
Servo C
出版信息
Acta Endocrinol Suppl (Copenh). 1980;238:133-7.
PMID:6933810
Abstract
Sorbitol and myoinositol have been measured from human cerebrospinal fluid. The normal concentrations are very small (below 100 microM/l). The detection limit of the Gas Liquid Chromatographic method was 5 microM/l. The sensitive method provided a possibility to compare quantitatively the sugar alcohol concentrations in human cerebrospinal fluid. Sorbitol concentration was increased and myoinositol concentration decreased in the cerebrospinal fluid of diabetic patients.
摘要
已对人脑脊液中的山梨醇和肌醇进行了测定。正常浓度非常低（低于100微摩尔/升）。气液色谱法的检测限为5微摩尔/升。这种灵敏的方法为定量比较人脑脊液中的糖醇浓度提供了可能。糖尿病患者脑脊液中的山梨醇浓度升高，而肌醇浓度降低。
相似文献
1
Sorbitol and myoinositol levels in the cerebrospinal fluid of diabetic patients.糖尿病患者脑脊液中的山梨醇和肌醇水平。
Acta Endocrinol Suppl (Copenh). 1980;238:133-7.
2
Polyols in the cerebrospinal fluid and plasma of neurological, diabetic and uraemic patients.神经疾病患者、糖尿病患者和尿毒症患者脑脊液及血浆中的多元醇
Acta Neurol Scand. 1977 Aug;56(2):111-6. doi: 10.1111/j.1600-0404.1977.tb01416.x.
3
Cerebrospinal fluid sorbitol and myoinositol in diabetic polyneuropathy.糖尿病性多发性神经病患者脑脊液中的山梨醇和肌醇
Acta Med Scand. 1977;202(4):301-4. doi: 10.1111/j.0954-6820.1977.tb16831.x.
4
Gas chromatographic separation and mass spectrometric identification of polyols in human cerebrospinal fluid and plasma.人脑脊液和血浆中多元醇的气相色谱分离与质谱鉴定
Acta Neurol Scand. 1977 Aug;56(2):104-10. doi: 10.1111/j.1600-0404.1977.tb01415.x.
5
Accumulation of myoinositol in plasma and red cells of diabetic patients.糖尿病患者血浆和红细胞中肌醇的蓄积。
Acta Med Scand. 1977 Jan;201(1-2):59-62. doi: 10.1111/j.0954-6820.1977.tb15655.x.
6
Cerebrospinal fluid polyols in patients with diabetes mellitus.糖尿病患者的脑脊液多元醇
Clin Chim Acta. 1973 Mar 30;44(3):437-42. doi: 10.1016/0009-8981(73)90089-2.
7
8
Monosaccharides and polyols in diabetes mellitus and uremia.糖尿病和尿毒症中的单糖和多元醇
J Lab Clin Med. 1973 Nov;82(5):809-17.
9
10
Variation in polyol levels in cerebrospinal fluid and serum in diabetic patients.糖尿病患者脑脊液和血清中多元醇水平的变化。
Diabetologia. 1975 Dec;11(6):575-80. doi: 10.1007/BF01222109.
引用本文的文献
1
Cerebrospinal fluid evidence of increased extra-mitochondrial glucose metabolism implicates mitochondrial dysfunction in multiple sclerosis disease progression.脑脊液中细胞外线粒体葡萄糖代谢增加的证据表明线粒体功能障碍与多发性硬化症疾病进展有关。
J Neurol Sci. 2008 Dec 15;275(1-2):106-12. doi: 10.1016/j.jns.2008.07.032. Epub 2008 Sep 9.
2
myo-Inositol and sorbitol in erythrocytes from diabetic patients before and after sorbinil treatment.糖尿病患者在服用索比尼尔治疗前后红细胞中的肌醇和山梨醇
Diabetologia. 1984 Nov;27(5):514-6. doi: 10.1007/BF00290386.
Zotero 插件