Samuelson K
Scand J Clin Lab Invest. 1980 May;40(3):289-91. doi: 10.3109/00365518009095581.
Radioimmunoassay (RIA) of cholic and chenodeoxycholic acid was compared to a total bile acid determination with 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD) and a gas liquid chromatographic (GLC) determination of individual bile acids. When sera from patients with increased bile acid concentration were analysed the results indicated a good correlation between GLC and the other methods. Analysis of sera from healthy subjects indicated a good correlation between GLC and RIA. There exists no correlation between RIA and 3 alpha-HSD when serum bile acids were analysed in healthy subjects in part due to the presence of varying amounts of secondary bile acids.
将胆酸和鹅去氧胆酸的放射免疫测定（RIA）与用3α-羟基类固醇脱氢酶（3α-HSD）进行的总胆汁酸测定以及对单个胆汁酸的气相色谱（GLC）测定进行了比较。当分析胆汁酸浓度升高患者的血清时，结果表明GLC与其他方法之间具有良好的相关性。对健康受试者血清的分析表明GLC与RIA之间具有良好的相关性。当对健康受试者的血清胆汁酸进行分析时，RIA与3α-HSD之间不存在相关性，部分原因是存在不同量的次级胆汁酸。
