Schroeder A, van der Zypen E, Stich H, Sutter F
J Maxillofac Surg. 1981 Feb;9(1):15-25. doi: 10.1016/s0301-0503(81)80007-0.
The results of a research project which has been under way for the last 7 years are reported. The project has been centred around a series of animal (monkey) experiments designed to test the suitability of cylindrical titanium implants with titanium-sprayed surfaces. The following results have been obtained: 1. The bone applies itself "ankylotically" (i.e. without an intervening layer of connective tissue) to the surface of the implant and, as revealed by observation over periods of up to 1 3/4 years, even remains attached to the implant surface when placed under load. 2. The fibres of the connective tissue between the bone and the epithelium insert into the titanium-sprayed surface and appear to be functionally orientated. 3. If the post of the implant is situated in a region of immobile, keratinized mucosa signs of adhesion of the epithelial cells to the titanium-sprayed surface become apparent. 4. The clinical success of the implant is clearly dependent on (a) the presence of tethered, immobile mucosa ("gingiva") around the post of the implant, and (b) perfect oral hygiene.
报告了一项过去7年一直在进行的研究项目的结果。该项目围绕一系列动物（猴子）实验展开，旨在测试表面喷涂钛的圆柱形钛植入物的适用性。已获得以下结果：1. 骨以“强直附着”的方式（即没有结缔组织中间层）附着于植入物表面，并且，通过长达1又3/4年的观察发现，即使在负载情况下，骨仍附着于植入物表面。2. 骨与上皮之间的结缔组织纤维插入喷涂钛的表面，并且似乎具有功能取向。3. 如果植入物的桩位于固定的角化黏膜区域，上皮细胞与喷涂钛表面的粘连迹象就会明显显现。4. 植入物的临床成功显然取决于：（a）植入物桩周围存在附着的、固定的黏膜（“牙龈”），以及（b）完美的口腔卫生状况。
