Miale J B
Scand J Haematol Suppl. 1980;37:21-33. doi: 10.1111/j.1600-0609.1980.tb01339.x.
Beginning in 1967, several committees have attempted to formulate a consensus opinion on how best to standardize the control of oral anticoagulant therapy. The three major proposals that evolved were: 1) to agree on a standard thromboplastin that would serve as a "reference thromboplastin", 2) to explore mathematical approaches for comparing the results obtained with various thromboplastins, and 3) the use of assayed plasmas that would serve as a common reference material for all thromboplastins. The advantages of reference plasmas as a common reference and their usefulness in the standardization of oral anticoagulant therapy are discussed.
从1967年开始，几个委员会试图就如何最好地规范口服抗凝治疗的控制达成共识意见。由此产生的三项主要提议是：1）就一种用作“参考凝血活酶”的标准凝血活酶达成一致；2）探索比较用各种凝血活酶获得的结果的数学方法；3）使用作为所有凝血活酶共同参考物质的经测定血浆。讨论了参考血浆作为共同参考的优点及其在口服抗凝治疗标准化中的用途。
