Bain B, Forster T, Sleigh B
Med J Aust. 1978 Nov 4;2(10):459-61. doi: 10.5694/j.1326-5377.1978.tb131641.x.
Six trromboplastins commonly used for prothrombin time determinations were studied. Prothrombin times of patients who were receiving oral anticoagulant therapy varied widely, depending on the origin of the thromboplastins. The therapeutic range which is recommended with one thromboplastin is often quite different from that recommended with another, and as a result, the therapeutic ranges of different institutions may show no overlap. Management of patients and comparison of therapeutic results would be facilitated if all thromboplastins in use in Australia were standardized by comparison with the Australian Reference Thromboplastin.
对常用于凝血酶原时间测定的六种凝血活酶进行了研究。接受口服抗凝治疗的患者的凝血酶原时间差异很大，这取决于凝血活酶的来源。一种凝血活酶推荐的治疗范围往往与另一种凝血活酶推荐的治疗范围有很大不同，因此，不同机构的治疗范围可能没有重叠。如果通过与澳大利亚参考凝血活酶比较，对澳大利亚使用的所有凝血活酶进行标准化，将有助于患者的管理和治疗结果的比较。
