不同人群中突变产生电泳变异体的速率是否存在差异？
Is there a difference among human populations in the rate with which mutation produces electrophoretic variants?
作者信息
Neel J V, Rothman E
出版信息
Proc Natl Acad Sci U S A. 1981 May;78(5):3108-12. doi: 10.1073/pnas.78.5.3108.
Abstract
Data are summarized that suggest that tropical-zone/tribal/nonindustrialized populations have higher frequencies of certain types of protein variants than temperate-zone/civilized/industrial populations, and it is demonstrated that these differences are not an artifact produced by the contagious type of sampling used with respect to tribal populations. Evidence is reviewed that suggests that a possible explanation of this difference is higher mutation rates in the tribal populations studied.
摘要
数据汇总表明，热带地区/部落/非工业化人群中某些类型蛋白质变体的频率高于温带地区/文明/工业化人群，并且证明这些差异并非因针对部落人群采用的传染性抽样类型而产生的人为现象。所审查的证据表明，这种差异的一种可能解释是，在所研究的部落人群中突变率较高。
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