Neel J V, Satoh C, Hamilton H B, Otake M, Goriki K, Kageoka T, Fujita M, Neriishi S, Asakawa J
Proc Natl Acad Sci U S A. 1980 Jul;77(7):4221-5. doi: 10.1073/pnas.77.7.4221.
A total of 289,868 locus tests, based on 28 different protein phenotypes and using one-dimensional electrophoresis to detect variant proteins, has yielded one probable mutation in the offspring of "proximally exposed" parents, who received an estimated average gonadal exposure of 31 to 39 rem in the atomic bombings of Hiroshima and Nagasaki. There were no mutations in 208,196 locus tests involving children of "distally exposed" parents, who had essentially no radiation exposure.
基于28种不同蛋白质表型并使用一维电泳检测变异蛋白质，总共进行了289,868次基因座检测，在广岛和长崎原子弹爆炸中估计平均性腺暴露量为31至39雷姆的“近端暴露”父母的后代中发现了一个可能的突变。在涉及“远端暴露”父母的孩子（基本上没有辐射暴露）的208,196次基因座检测中未发现突变。
