[蒽环类药物给药后骨髓和脾脏造血干细胞的行为]
[Behaviour of bone marrow and splenic hemopoietic stem cells following administration of anthracyclines].
作者信息
Massa G, Bogliolo G, Ghio R, Muzzulini C, D'Amore F
出版信息
Boll Soc Ital Biol Sper. 1981 Jun 30;57(12):1311-5.
PMID:6945864
Abstract
The effect of Adriamycin and 4-Eip-Adriamycin was studied on CFUs, CFUc, CFUe of murine bone marrow and spleen. Differences among the bone marrow stem cells and the spleen stem cells have been observed. It seems possible to explain some of these differences admitting a process of redistribution from the bone marrow to the spleen.
摘要
研究了阿霉素和4-表异构阿霉素对小鼠骨髓和脾脏的集落形成单位（CFUs）、粒系集落形成单位（CFUc）、红系集落形成单位（CFUe）的影响。已观察到骨髓干细胞和脾脏干细胞之间的差异。通过承认从骨髓到脾脏的重新分布过程，似乎有可能解释其中一些差异。
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